T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure
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چکیده
منابع مشابه
T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure
Alterations of the β-adrenergic signalling, structural remodelling, and electrical failure of T-tubules are hallmarks of heart failure (HF). Here, we assess the effect of β-adrenoceptor activation on local Ca(2+) release in electrically coupled and uncoupled T-tubules in ventricular myocytes from HF rats. We employ an ultrafast random access multi-photon (RAMP) microscope to simultaneously reco...
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Division of Cardiovascular Medicine, Dept of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA; Shanghai First People’s Hospital, Shanghai Jiaotong University, Shanghai, China; Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN; Dept of Pharmacology, College of Basic Medicine, Anhui Medical University, Hefei, China; Dept of Physiology & Biophysics, Univ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2016
ISSN: 1422-0067
DOI: 10.3390/ijms17091471